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Performance CE | Unusually high  Time to First Byte

Question asked by Shailendu Verma on Jul 20, 2015
Latest reply on Jul 20, 2015 by David Tam
I have a SugarCRM CE 6.5x installation with 8 GB RAM for PHP server and another 8 GB server RAM for mySQL. 

We have the problem that sometimes the instance is taking just too long to navigate. When we analyzed using Performance Analyzer Chrome extension, it shows a very high Time to First Byte (ranging between 8 - 80 seconds) at different times. 

Has someone every experienced such problem?  Any pointers would a greatly appreciated!